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Science Park Informatics

Triplex-forming Oligonucleotide Search Engine

The Triplex-forming Oligonucleotide Target Sequence Search Engine searches gene sequences for potential TFO target sequences matching user-specified criteria, including length and base composition. The engine gives the user the option to choose whether to search a raw genomic sequence or a repeat-masked sequence. Search results list the TFO target sequences found along with descriptive information about them, including length, percent G, position on the chromosome, gene region in which they were found, matches to known repeat sequences, and PubMed identifiers for articles reporting validated TFO target sequences. The search results are enriched with links to NCBI resources: Entrez Gene, GenBank, BLAST, and PubMed.